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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COIL
All Species:
4.55
Human Site:
S222
Identified Species:
12.5
UniProt:
P38432
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38432
NP_004636.1
576
62608
S222
R
C
S
S
P
K
G
S
A
R
N
S
L
V
K
Chimpanzee
Pan troglodytes
XP_511900
576
62664
S222
R
C
S
S
P
K
G
S
A
R
N
S
L
V
K
Rhesus Macaque
Macaca mulatta
XP_001104670
575
62725
G221
Q
R
C
S
S
P
K
G
S
A
R
N
S
L
V
Dog
Lupus familis
XP_537686
578
63266
P223
G
G
P
P
K
G
S
P
A
R
S
S
L
I
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_057915
573
62245
P222
A
S
Q
N
C
S
F
P
R
A
S
P
R
S
L
Rat
Rattus norvegicus
NP_059056
569
62416
R220
S
Q
N
C
S
F
P
R
A
S
Y
R
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415654
600
64190
G222
K
A
A
H
G
R
V
G
G
S
A
P
L
M
A
Frog
Xenopus laevis
Q09003
536
59502
C197
P
D
K
H
S
R
K
C
P
P
Q
A
S
N
K
Zebra Danio
Brachydanio rerio
NP_571587
528
57977
K189
S
A
V
A
F
S
D
K
T
N
R
T
K
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.8
74.9
N.A.
66.1
65.4
N.A.
N.A.
37.5
37.8
37.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.6
84
N.A.
77.4
77.9
N.A.
N.A.
53.6
55.9
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
33.3
N.A.
0
6.6
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
46.6
N.A.
13.3
13.3
N.A.
N.A.
33.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
12
12
0
0
0
0
45
23
12
12
0
0
12
% A
% Cys:
0
23
12
12
12
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
12
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
12
12
23
23
12
0
0
0
0
0
0
% G
% His:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
12
0
12
0
12
23
23
12
0
0
0
0
12
0
45
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
45
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
12
12
0
0
0
0
0
12
23
12
0
23
0
% N
% Pro:
12
0
12
12
23
12
12
23
12
12
0
23
0
0
0
% P
% Gln:
12
12
12
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
23
12
0
0
0
23
0
12
12
34
23
12
12
0
0
% R
% Ser:
23
12
23
34
34
23
12
23
12
23
23
34
34
23
0
% S
% Thr:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% T
% Val:
0
0
12
0
0
0
12
0
0
0
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _